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Cas 123-75-1 API Raw Material Pyrrolidine C4H9N 99% High Purity

Basic Information
Place of Origin: China
Brand Name: First
Certification: COA
Model Number: 123-75-1
Minimum Order Quantity: 1KG
Price: 50-100USD
Packaging Details: 1kg/bag ;25kg/drum,25 kg/Carton
Delivery Time: 5 to 10 days
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram,BTC
Supply Ability: 1000 Tons
Detail Information
Product Name: Pyrrolidine Cas No.: 123-75-1
Einecs No.: 204-648-7 Mf: C4H9N
Purity: 99.0%min Appearance: Colorless Liquid
Boiling Point: 87-88 °C/760 MmHg (lit.) Density: 0.852 G/mL At 25 °C (lit.)
Sample: Availiable Other Names: TETRAMETHYLENEIMINE;pyrrolidine,tetrahydropyrrole
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Cas 123-75-1


API Raw Material Cas 123-75-1



Product Description

Pyrrolidine Basic information




Product Name: Pyrrolidine
CAS: 123-75-1
MW: 71.12
EINECS: 204-648-7
Mol File: 123-75-1.mol
Pyrrolidine Structure



Pyrrolidine Chemical Properties


Melting point -63 °C
Boiling point 87-88 °C/760 mmHg (lit.)
density 0.852 g/mL at 25 °C (lit.)
vapor density 2.45 (vs air)
vapor pressure 128 mm Hg ( 39 °C)
refractive index n20/D 1.443(lit.)
Fp 37 °F
storage temp. Store below +30°C.
solubility water: miscible
form Liquid
pka 11.27(at 25℃)
color Colorless to Almost colorless
Odor at 0.10 % in propylene glycol. ammoniacal animal egg amine
PH 12.9 (100g/l, H2O, 20℃)
explosive limit 1.6-10.6%(V)
Odor Type ammoniacal
Water Solubility Miscible with alcohol, ether, chloroform and water.
Sensitive Air Sensitive
Merck 14,8015
JECFA Number 1609
BRN 102395
Stability: Stable; flammable. Incompatible with strong acids, strong oxidizing agents.
LogP 0.22 at 25℃




Pyrrolidine Usage And Synthesis


Uses: Pyrrolidine is a flammable alkaline liquid that undergoes reactions typical of secondary amines. It is used to prepare pesticides and rubber accelerators and as a chemical intermediate (usually the hydrochloride form) in the pharmaceutical industry. There is relatively limited industrial exposure to this material.


Chemical Properties Pyrrolidine appears as a colorless to pale yellow liquid with an ammonia-like odor. It is infinitely miscible with water and conventional organic solvents such as methanol, acetone, ether, and chloroform. It acts as a lachrymator.
Chemically, pyrrolidine behaves like a secondary amine in every respect. For example, it undergoes Leuckart –Wallach and Mannich reactions and is readily converted into an enamine. In the presence of a catalyst, such as platinum at 360°C or rhodium at 650°C, pyrrole is formed. In the presence of a copper catalyst, N-methylpyrrolidone is converted into N-methylpyrrolidine.
Application Pyrrolidine is a heterocyclic compound used as a building block in the synthesis of wide range of pharmaceutical compounds, namely matrix metalloprotein inhibitors (MMPIs) and aminopeptidase N inhibitors (APNIs). It has been used for the synthesis of N-benzoyl pyrrolidine from benzaldehyde via oxidative amination. It may be used as a catalyst for the synthesis of N-sulfinyl aldimines from carbonyl compounds and sulfonamides.
Pyrrolidine can also be used to synthesize:
Taddol-pyrrolidine phosphoramidite, a ligand for rhodium-catalyzed [2+2+2] cycloaddition of pentenyl isocyanate and 4- ethynylanisole.
H,4 PyrrolidineQuin-BAM (′PBAM′), a selective catalyst for the aza-Henry addition of nitroalkanes to aryl aldimines.
1,2,3,3a,4,9-Hexahydropyrrolo[2,1-b]quinazoline by reacting with o-aminobenzaldehyde.


Cas 123-75-1 API Raw Material Pyrrolidine C4H9N 99% High Purity 1

Cas 123-75-1 API Raw Material Pyrrolidine C4H9N 99% High Purity 2

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